Indian J Physiol Pharmacol. Oct;45(4) In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves. Singh B(1). Request PDF on ResearchGate | Hepatoprotective activity of Eclipta alba Hassk. against paracetamol induced hepatocellular damage in mice | The effect of. The hepatoprotective activity of different extracts of whole plant Eclipta alba was investigated against CCl4 induced hepatic damage inmale albino rat.

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Effects of silymarin nanoemulsion against carbon tetrachloride-induced hepatic damage.

Similar results have been observed by Pattanayak and Priyashree which have noticed such changes in the hepatotoxic animal when treated with the extract from Dendrophoe falcanta. April 04, Published online on: Chandra T, Sadique J. Hence, the study was conducted to elucidate the hepatoprotective activity of aqueous extract of traditional medicinal plant Eclipta alba against carbon tetrachloride CCl4 induced toxicity in male albino rats.

February 12, Manuscript accepted on: The hepatoprotective effect of hepagoprotective aqueous extracts of E.

Serum was prepared from the collected blood and subjected to biochemical estimation of different parameters like aspartate aminotransferase ASTalanine aminotransferase ALTalkaline phosphatase ALPtotal lipid, triglceride, phosphatase and cholesterol.

Liver homogenates were also ec,ipta to various biochemical estimation. J Ayurveda Integr Med.

The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4| Abstract

Suresh Kumar and Mishra have also reported hepatoprotective effect of Pergularia demia ethanol extract. Copy the following to cite this URL: This work is licensed under a Creative Commons Attribution 4. However, the dose adjustments may be necessary to optimize the similar hepatoprotective efficacy in clinical settings.


Hassk has been widely used in India for the traditional treatment of liver disorders Chopra et al.

Despite the tremendous scientific advancement in the field of gastroenterology over the recent years, there is not even a single effective allopathic medication available for the treatment of liver disorders. Protective effects of silymarin, a milk thistle Silybium marianum derivative on ethanol-induced oxidative stress in liver.

The observations of these dose, clearly indicat the involvement of heptoprotective active principles in Eclipta alba. They were then mechanically powdered and sieved. Similarly, level of triglyceride, total lipid and cholesterol was found to be decresed after the treatment.

Total biochemical parameters was recorded acitvity the present study. J Biochem Mol Toxicol. Biomed Pharmacol J ;1 1. Rest parameters were found to be all most normal level when three different doges of the compound of the Eclipta alba were given to the CCl4 induced hepatotoxic rat. Water was supplied libitum.

Hepatoprotective activity of Leptadenia reticulata stems wclipta carbon tetrachloride-induced hepatotoxicity in rats. Hepatoprotective activity of the edible snail Bellamia bengalensis flesh extract in carbon tetrachloride induced hepatotoxicity in rats.

In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

A preliminary phytochemical screening was carried out for the extracts employing the standard procedure to reveal the presene of alkaloids, steroids, terpenes, flavonoid, saponins, tennins, glycosides, carbohydrates and proteins.

Twenty four albino rats of wistar albino rats weighing gm were obtained from laboratory abla college. Copy the following to cite this article: A few photomicrographs of representative types were also taken. Rats were hepatoprtective in to six groups of 6 rats each as follows.


In vivo hepatoprotective activity of active fraction from ethanolic extract of Eclipta alba leaves.

Vanukumar and Latha have also reported that when liver cell plasma membrene is damaged, a variety of enzymes normally located in the cytosol which are released in blood stream which causes hepatocellular changes.

The protective effect of Eclipta alba on carbon tetrachloride-induced acute liver damage. The liver tissue was dissected by blotting of the blood washed in saline. But it was noiticed that the recovery beginning as soon as the plant extract was given. The level of total protein was found to be at normal level after the treatment. They were fed with pallets of Golden feed, New Delhi. Indian herbal medicines in the treatment of liver diseases: Protective effects of pterostilbene against acetaminophen-induced hepatotoxicity in rats.

The possible hepatoprotective activity of Eclipta alba whole plant extract against CCl4

Email this article Login required. Hepatoprotective activity of Eclipta alba against carbon tetrachloride-induced hepatotoxicity in albino rats. Hepatoprotective effect of poly herbal formulation against various hepatotoxic agents in rats.